Related Experiment Video

Updated: Aug 11, 2025

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

3.7K

Utilization of TandemHeart in cardiogenic shock: Insights from the THEME registry

Michael Megaly1, Chaun Gandolfo1, Samer Zakhour1

  • 1Division of Cardiology, Henry Ford Health System, Detroit, Michigan, USA.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|February 7, 2023
PubMed

Insights

TandemHeart device implantation in cardiogenic shock patients showed a 74% 30-day survival rate. This study highlights the device

Area of Science:

  • Cardiology
  • Medical Devices
  • Critical Care Medicine

Background:

  • TandemHeart has previously shown efficacy in managing cardiogenic shock (CS) complications.
  • Contemporary real-world outcomes for TandemHeart in CS patients require updated reporting.

Purpose of the Study:

  • To evaluate the real-world effectiveness and outcomes of the TandemHeart device in contemporary patients with cardiogenic shock.
  • To assess hemodynamic improvements and survival rates associated with TandemHeart use.

Main Methods:

  • A prospective, observational study (THEME registry) analyzed 50 patients treated with TandemHeart.
  • Data collected included baseline characteristics, hemodynamic changes, and patient outcomes.
  • Implantation timing relative to CS diagnosis was recorded.

Main Results:

  • Cardiac index significantly improved 24 hours post-implantation (median change 1.0 L/min/m²).
  • Survivors demonstrated improved cardiac index and lactate clearance.
  • 30-day and 180-day survival rates were 74% and 66%, respectively.
  • Patients using TandemHeart as a bridge to surgery had an 85% 180-day survival rate.

Conclusions:

  • TandemHeart use in a contemporary CS cohort is associated with significant survival benefits.
  • The device demonstrates favorable outcomes, including high 30-day and 180-day survival rates.
  • TandemHeart is a viable option for managing cardiogenic shock, including as a bridge to surgery.
Abstract

Keywords:
CSTandemHeartTandemLifecardiogenic shock

More Related Videos

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.3K
Implantation of Total Artificial Heart in Congenital Heart Disease07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

24.7K

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
19
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
20
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
31
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
19
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
31
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
24