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Monkeypox-induced proctitis: a case report of an emerging complication
Azeem Rathore1, Cameron Kahn2, Daniel Reich3
1Department of Medicine, University of Florida Health Science Center, Jacksonville, FL, 32209, USA. azeem.rathore@jax.ufl.edu.
Infection
|February 7, 2023
Summary
Monkeypox can present atypically, including as proctitis, diverging from historical rash patterns. Early recognition and treatment are crucial for managing this evolving zoonotic disease.
Area of Science:
- Infectious Diseases
- Dermatology
- Public Health
Background:
- The 2022 human monkeypox virus outbreak presented with atypical symptoms beyond the historically recognized rash illness.
- Previous cases typically showed rashes on the face, palms, and soles, with nonspecific symptoms like fever and lymphadenopathy.
Observation:
- A case report details a 32-year-old male with HIV experiencing worsening rectal pain and diffuse skin lesions, including on hemorrhoids.
- Imaging revealed rectal thickening consistent with proctitis, and PCR testing confirmed monkeypox infection.
Findings:
- The patient received a 14-day course of tecovirimat for disseminated monkeypox infection.
- The patient showed improved pain control and was discharged after initiating antiviral treatment.
Implications:
- Clinicians must consider monkeypox in the differential diagnosis for proctitis due to emerging atypical presentations.
- Further development of evidence-based treatment protocols is needed for managing monkeypox-associated proctitis and other atypical manifestations.
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