Related Experiment Video
Updated: Aug 11, 2025

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Infective endocarditis of quadricuspid aortic valve.
Ariana M Goodman1, Hossein Amirjamshidi1, Daniel R Ziazadeh1
1Department of Surgery Division of Cardiac Surgery, University of Rochester Medical Center, Box: Surg 601 Elmwood Ave, Rochester, NY, 14642, USA.
Infective endocarditis in rare quadricuspid aortic valves can be successfully treated with surgical aortic valve replacement. This procedure is safe and effective, even in patients with complex medical histories.
Area of Science:
- Cardiology
- Cardiac Surgery
- Infectious Diseases
Background:
- Infective endocarditis commonly affects the aortic valve, often requiring surgery.
- Quadricuspid aortic valves are rare anomalies, typically asymptomatic and less prone to severe complications.
- Limited literature exists on infective endocarditis specifically in quadricuspid aortic valves.
Observation:
- A case of infective endocarditis in a 30-year-old male with a quadricuspid aortic valve is presented.
- The patient had a history of polysubstance use, upper extremity aneurysm, and previous tricuspid valve endocarditis.
- Surgical aortic valve replacement was performed using a 25 mm bioprosthetic tissue valve via median sternotomy.
Findings:
- The patient recovered fully after aortic valve replacement and antibiotic treatment.
- Discharge occurred without any complications, indicating a successful outcome.
- This case demonstrates the feasibility and safety of surgical aortic valve replacement for infective endocarditis in quadricuspid valves.
Implications:
- Surgical aortic valve replacement is a viable treatment option for infective endocarditis in quadricuspid aortic valves.
- This approach offers a safe and effective solution, even in patients with pre-existing conditions.
- Further research into managing rare aortic valve anomalies like quadricuspid valves is warranted.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Aortic Regurgitation I: Introduction
Endocarditis IV: Nursing Management
Rheumatic Heart Disease I: Introduction

