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Bronchial Asthma Exacerbation in the Emergency Department in a Saudi Pediatric Population: An Insight From a Tertiary
Mohammed A Alfurayh1, Mouath A Alturaymi1, Ahmed Sharahili1
1Medicine and Surgery, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Riyadh, SAU.
Insights
Severe uncontrolled asthma in children presents significant challenges, leading to increased emergency room visits and hospital admissions. Effective management and understanding of comorbidities are crucial for better pediatric asthma control.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Clinical Pediatrics
Background:
- Severe uncontrolled asthma poses a significant challenge in pediatric care, associated with high morbidity and mortality.
- Children with severe asthma face risks including adverse effects, life-threatening exacerbations, and diminished quality of life.
- Asthma exacerbations in children necessitate frequent emergency room (ER) visits and hospitalizations.
Purpose of the Study:
- To analyze the characteristics and outcomes of pediatric patients presenting with asthma exacerbations to the ER.
- To identify factors associated with increased healthcare utilization for pediatric asthma.
- To investigate the role of comorbidities in the management of severe pediatric asthma.
Main Methods:
- A retrospective cohort study was conducted at National Guard Health Affairs Hospital, Riyadh, Saudi Arabia.
- Data from 363 pediatric patients (1 month to 14 years) who visited the ER for asthma exacerbation between January 2016 and May 2022 were reviewed.
- Variables included demographics, comorbidities (e.g., congenital heart disease, GERD, diabetes), asthma history, and medication use.
Main Results:
- The study analyzed 363 pediatric patients (63.1% male), with a mean age of 4.9 years.
- Common presenting symptoms included cough (88.2%), shortness of breath (59%), and fever (46%).
- Inhaled corticosteroids were linked to reduced ER visits and nocturnal symptoms; 44 patients required hospital admission.
Conclusions:
- Pediatric asthma remains a substantial public health concern, with rising rates of hospital admissions and ER visits.
- Comorbidities such as obesity and gastroesophageal reflux disease significantly impact asthma control in children.
- Optimizing asthma management in pediatric populations requires addressing underlying comorbidities and ensuring consistent treatment adherence.
Abstract:
Background Severe uncontrolled asthma in the pediatric population is a complicated disease and is considered a major challenge for pediatricians. Severe bronchial asthma in the pediatric population is related to significant morbidity and mortality. Children with complicated asthma are at a higher risk for unfavorable outcomes, including medication-associated adverse effects, severe life-threatening exacerbations, and poor quality of life. Methodology A cohort study was conducted at National Guard Health Affairs Hospital in Riyadh, Saudi Arabia. Data were collected using the chart review method utilizing a data collection sheet. A total of 363 charts of children aged one month to 14 years who visited the emergency room (ER) due to asthma exacerbation at NGHA were reviewed, from January 2016 to May 2022, to extract the variables. Variables included demographic data, comorbidities, and asthma-related variables which included the number of asthma exacerbations, hospital admission, ER visit, medication use (non-steroidal anti-inflammatory drugs and steroids), and the presence of allergic rhinitis and eczema. Results A total of 363 patients were analyzed, with 229 (63.1%) males and 134 (36.9%) females. The mean age was 4.9 years (SD = 3.5 years). Overall, 8.5% of patients had congenital heart disease, 4.1% had gastroesophageal reflux disease, 2.2% had diabetes mellitus, 1.9% had obstructive sleep apnea, and 0.6% had hypertension. Most patients presented with a cough at 88.2% (n = 320), followed by shortness of breath at 59% (n = 214) and fever at 46% (n = 167). Male asthmatics visited ER more than females. Forty-four patients were admitted to the hospital. Inhaled steroids were associated with fewer emergency department visits and night symptoms. Most asthmatic patients presented in the winter and fall seasons. Conclusions Asthma is a common pediatric respiratory disease that could be a burden if not controlled well. Unfortunately, the frequency of hospital admissions and pediatric ER visits due to asthma exacerbation is increasing. Comorbidities such as obesity and gastroesophageal reflux disease play a significant role in asthma control.
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