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Updated: Aug 11, 2025
Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
Positive outcome of nonoperative management of spinal cord compression by multiple myeloma: A case report
Fresnel Lutèce Ontsi Obame1, Yao Christian Hugues Dokponou1, Jawad Laaguili1
1Department of Neurosurgery, Mohammed V Faculty of Medicine and Pharmacy of Rabat, Military Teaching Hospital Mohammed V of Rabat, Morocco.
Background:
Spinal cord compression (SCC) is a severe consequence of multiple myeloma (MM). Surgical management is appropriate when there are spinal instability and neurological function compromise. The reversibility of peripheral neuropathy during treatment of MM has been reported in some studies after a cycle of Bortezomib (Velcade), Thalidomide, and Dexamethasone (VTD), but very rare in myeloma patients with SCC.
Case Description:
We report a case of a 58-year-old male tetraplegic secondary to cervical SCC by MM who completely recovered after 5 cycles of VTD chemotherapy without surgery.
Conclusion:
Surgical spinal cord decompression by laminectomy is known as the gold standard for treating this condition. Nevertheless, some patients can completely recover from nervous insult without surgery.
