Related Experiment Video
Updated: Aug 11, 2025

12:01
The Superficial Inferior Epigastric Artery Fascia Flap for Nerve Reconstruction in Rabbits
Published on: June 13, 2025
238
Regional flap: A reliable coverage for post-radiation ulcer.
Wenfang Dong1, Xinling Zhang1, Xiuzhen Luo2
1Department of Plastic and Reconstructive Surgery, Peking University Third Hospital, Beijing, China.
International Wound Journal
|February 8, 2023
Summary
Regional flaps offer a safe and effective solution for treating radiation-damaged tissue ulcers. This 10-year study shows a 100% success rate with no recurrence, demonstrating their efficacy in reconstructive surgery.
Area of Science:
- Plastic Surgery
- Reconstructive Surgery
- Oncology
Background:
- Radiation-induced ulcers present a significant clinical challenge with limited treatment options.
- Effective reconstruction of these ulcers is crucial for patient quality of life.
Purpose of the Study:
- To evaluate the safety and efficacy of regional flaps for managing post-radiation ulcers.
- To analyze a decade of clinical experience with this reconstructive technique.
Main Methods:
- Retrospective analysis of 13 patients with post-radiation ulcers treated between 2012 and 2022.
- Reconstruction involved complete excision of irradiated tissue and coverage with well-vascularized flaps (local, regional, free).
- Outcomes assessed included complications, reoperation rates, flap success, and recurrence.
Main Results:
- Eleven patients underwent reconstruction with 15 regional flaps and 3 local flaps.
- The overall success rate for regional flaps was 100%, with no observed recurrence after a mean follow-up of 23.3 months.
- Complications included wound dehiscence (6.7%) and localized necrosis (26.7%) in regional flaps, necessitating reoperation in some cases.
Conclusions:
- Regional flaps are a safe and effective reconstructive method for patients suffering from post-radiation ulcers.
- This approach demonstrates high success rates and low recurrence, addressing a critical need in managing radiation-damaged tissue.
Related Concept Videos
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
615
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
615
Peripheral Artery Disease V: Postoperative Nursing Management
16
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
16

