Related Experiment Video
Updated: Aug 11, 2025

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
Skeletal and Dental Fractures Associated With Electroconvulsive Therapy
1Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bangalore, India (candrade@psychiatrist.com).
Electroconvulsive therapy (ECT) can cause muscle contractions leading to injuries. Modifying ECT with muscle relaxants significantly reduces these risks, making it safe for most patients.
Area of Science:
- Neurology
- Psychiatry
- Anesthesiology
Background:
- Electroconvulsive therapy (ECT) can induce intense motor seizures.
- These seizures cause forceful muscle contractions, increasing the risk of skeletal and dental injuries.
- The motor component of the seizure is not essential for therapeutic efficacy.
Purpose of the Study:
- To evaluate the safety of modified ECT in terms of skeletal and dental risks.
- To assess the incidence of fractures and dental injuries associated with modified ECT procedures.
- To identify factors influencing the risk of complications during ECT.
Main Methods:
- Review of population-based data on fracture and dental injury rates.
- Analysis of risk factors, including patient comorbidities and ECT procedure modifications.
- Examination of anecdotal reports concerning high-risk patients.
Main Results:
- Modified ECT, utilizing muscle relaxants, markedly reduces muscle contractions and associated risks.
- Population-based data indicate very low fracture risk (0.36 per 100,000 ECTs in recent data) and dental fracture risk (0.02% per ECT).
- Preexisting conditions increase risk, while proper seizure modification and protective measures decrease it.
Conclusions:
- Well-modified ECT is associated with minimal skeletal and dental risks, even in high-risk patients.
- Careful patient assessment and meticulous ECT technique are crucial for minimizing complications.
- Optimizing ECT practice ensures patient safety and reduces the likelihood of fractures and dental injuries.
More Related Videos
09:16Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
Published on: June 21, 2019
04:51Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
Related Concept Videos
Electroconvulsive Therapy
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...