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Liquid Biopsies for Cancer Genotyping: Coming of Age?
Anders Jacobsen Skanderup1,2, Su Fen Ang1, Daniel S W Tan1,2
1Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, Singapore.
Abstract:
Precision oncology is predicated on optimal molecular profiling that is "fit for purpose" to identify therapeutic vulnerabilities. Liquid biopsies may compensate for inadequate genotyping, but remain less sensitive and specific compared with tissue biopsies. The liquid biopsy toolbox is poised to expand through novel assays and insights from longitudinal profiling. See related article by Sugimoto et al., p. 1506.
