Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Morphometry in surgical pathology.

S H Paplanus1, A R Graham

  • 1Department of Pathology, University of Arizona Health Sciences Center, Tucson 85724.

Analytical and Quantitative Cytology and Histology
|October 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Poisoning by White Precipitate.

British medical journal·2010
Same author

Mongolism in One of Twins.

British medical journal·2010
Same author

Telepathology overview: from concept to implementation.

Human pathology·2002
Same author

Ludwig's angina: report of a case and review of management issues.

The Annals of otology, rhinology, and laryngology·2001
Same author

The lower limb in people with diabetes. Position statement of the Australian Diabetes Society.

The Medical journal of Australia·2000
Same author

Telepathology: a ten-year progress report.

Human pathology·1997
Same journal

Micronuclei and other nuclear anomalies in buccal mucosa following exposure to X-ray radiation.

Analytical and quantitative cytology and histology·2012
Same journal

Color deconvolution. Optimizing handling of 3D unitary optical density vectors with polar coordinates.

Analytical and quantitative cytology and histology·2012
Same journal

Nuclear morphometry in the differential diagnosis of eosinophilic renal epithelial tumors.

Analytical and quantitative cytology and histology·2012
Same journal

Spectrum of prostatic nonepithelial tumors and tumorlike conditions with spindle cell features.

Analytical and quantitative cytology and histology·2012
Same journal

A framework for quantitative assessment of Ki67 distribution in preneoplastic bronchial epithelial lesions.

Analytical and quantitative cytology and histology·2012
Same journal

Classification and grading of noninvasive and invasive neoplasms of the urothelium.

Analytical and quantitative cytology and histology·2012
See all related articles

Morphometry, the study of shape and form, enhances surgical pathology diagnoses by improving the identification and differentiation of various cellular and tissue abnormalities. This quantitative approach aids pathologists in achieving greater diagnostic accuracy and precision.

Area of Science:

  • Surgical Pathology
  • Quantitative Morphology
  • Diagnostic Histopathology

Background:

  • Morphometry offers a quantitative approach to analyzing cellular and tissue structures.
  • Traditional histopathological evaluation can be subjective, leading to diagnostic challenges.
  • Advances in imaging and computational tools facilitate morphometric analysis.

Purpose of the Study:

  • To discuss the potential applications of morphometry in surgical pathology.
  • To highlight specific areas where morphometry can aid in diagnosis and prognosis.
  • To emphasize the integration of morphometric data with clinical information for improved diagnostic accuracy.

Main Methods:

  • Application of quantitative measurements to cellular and nuclear parameters.

Related Experiment Videos

  • Analysis of histologic sections for features like lesion thickness and glandular architecture.
  • Utilizing morphometric techniques in DNA ploidy analysis.
  • Correlating morphometric findings with clinical data and prognostic outcomes.

    • Main Results:

    • Morphometry aids in identifying malignancy in predominantly benign lesions (e.g., thyroid neoplasms).
    • It helps define reference points in disease continua (e.g., colon cancer progression).
    • Distinguishes between similar benign and malignant lesions (e.g., fibromatosis vs. fibrosarcoma).
    • Differentiates between similar malignant neoplasms (e.g., small-cell lung carcinoma vs. lymphoma).
    • Morphometric parameters provide prognostic information (e.g., nuclear roundness in prostate cancer).

    Conclusions:

    • Morphometry enhances the observation and interpretation of morphologic features in surgical pathology.
    • Integration of morphometry with clinical data and pathologist expertise increases diagnostic accuracy and precision.
    • Morphometry is increasingly applied to histologic sections for diagnostic and prognostic purposes.