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Monkeypox virus: A review.

Arash Letafati1, Tannaz Sakhavarz2

  • 1Virology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Microbial Pathogenesis
|February 9, 2023
PubMed
Summary

Monkeypox, a virus related to smallpox, is spreading globally. While there is no cure, supportive care and antiviral medications can manage symptoms.

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Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • Monkeypox is a zoonotic virus belonging to the Orthopoxvirus genus.
  • Global cases have surged beyond endemic regions, prompting international concern.
  • The virus is related to smallpox and was first identified in monkeys.

Purpose of the Study:

  • To provide a comprehensive overview of monkeypox.
  • To discuss viral structure, transmission, replication, and clinical features.
  • To review current global prevalence, vaccination, and treatment strategies.

Main Methods:

  • Literature review and synthesis of existing data.
  • Analysis of viral characteristics and transmission dynamics.
  • Examination of clinical manifestations and management approaches.
Keywords:
Emerging virusesMonkeypoxPandemicPoxviridaeRe-emerging viruses

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Main Results:

  • Monkeypox spreads through respiratory droplets and direct contact with lesions.
  • Supportive care is the primary treatment, with antivirals like tecovirimat used in severe cases.
  • There is a lack of established guidelines for symptom management.

Conclusions:

  • Understanding monkeypox is crucial for future research and public health interventions.
  • Further studies are needed to establish clear management guidelines.
  • Global cooperation is essential to monitor and control the spread of monkeypox.