Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

87
Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
87
Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

94
During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
94
Role of Amygdala in Memory01:16

Role of Amygdala in Memory

337
The amygdala is a small, almond-shaped structure responsible for processing and storing memories, particularly those linked to emotions like fear and stress. It plays an essential role in the brain's response to emotionally significant events and often enhances memory formation by triggering stress hormone release. The amygdala is vital for encoding and retrieving memories associated with fear or stress, a process that is adaptive by helping organisms avoid dangerous situations.
One of the...
337
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

3.3K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
3.3K
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

140
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
140
Socioemotional Experience and Gender Development01:30

Socioemotional Experience and Gender Development

59
Social-emotional experiences and cultural influences play significant roles in shaping gender development. During middle childhood, from ages 6 to 11, peer groups become dominant in reinforcing gender norms. Children in this age group often align with same-gender peer groups, which actively encourage behaviors that conform to traditional gender roles. For instance, boys may be discouraged from engaging in activities perceived as feminine, reinforcing culturally dictated norms about masculinity...
59

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lifestyle habits and type 2 diabetes traits in patients from healthcare centers in Dubai, United Arab Emirates: a cross-sectional study.

Frontiers in endocrinology·2025
Same author

PPAR agonists as add-on treatment with metformin in management of type 2 diabetes: a systematic review and meta-analysis.

Scientific reports·2024
Same author

Exploratory genetic analysis in children with autism spectrum disorder and other developmental disorders using whole exome sequencing.

Biomolecules & biomedicine·2024
Same author

What maternal educational mobility tells us about the mother's parenting routines, offspring school achievement and intelligence.

Social science & medicine (1982)·2024
Same author

Effects of Pre- and Postnatal Early-Life Stress on Internalizing, Adiposity, and Their Comorbidity.

Journal of the American Academy of Child and Adolescent Psychiatry·2023
Same author

Effects of combined treatment of probiotics and metformin in management of type 2 diabetes: A systematic review and meta-analysis.

Diabetes research and clinical practice·2023

Related Experiment Video

Updated: Aug 11, 2025

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.0K

Excessive Crying, Behavior Problems, and Amygdala Volume: A Study From Infancy to Adolescence.

Sara Sammallahti1, Fadila Serdarevic2, Henning Tiemeier3

  • 1Erasmus MC, Sophia Children's Hospital, Rotterdam, the Netherlands; University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Journal of the American Academy of Child and Adolescent Psychiatry
|February 9, 2023
PubMed
Summary

Excessive infant crying and irritability are linked to later behavioral issues and smaller amygdala volume in children. This suggests early neurobiological differences may underlie these developmental pathways.

Keywords:
amygdalabehavioral problemcryingmagnetic resonance imaging

More Related Videos

Chronic Social Defeat Stress in Early Adolescent Male Mice
07:06

Chronic Social Defeat Stress in Early Adolescent Male Mice

Published on: January 24, 2025

711
Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

1.7K

Related Experiment Videos

Last Updated: Aug 11, 2025

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.0K
Chronic Social Defeat Stress in Early Adolescent Male Mice
07:06

Chronic Social Defeat Stress in Early Adolescent Male Mice

Published on: January 24, 2025

711
Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

1.7K

Area of Science:

  • Developmental neuroscience
  • Child and adolescent psychology
  • Neuroimaging research

Background:

  • Excessive infant crying is a common concern, potentially linked to later behavioral problems.
  • Understanding the neurobiological underpinnings of infant crying and irritability is crucial for early risk identification.
  • Previous research suggests a connection between early-life stress and later neurodevelopmental outcomes.

Purpose of the Study:

  • To investigate the association between excessive crying and irritability in infancy with behavioral problems in childhood and adolescence.
  • To examine the relationship between early crying/irritability and amygdala volume in children and adolescents.
  • To explore potential neurobiological mechanisms linking infant behavior to later developmental trajectories.

Main Methods:

  • A prospective, population-based cohort study of 4,751 children (Generation R Study).
  • Parent-rated assessments of excessive crying and irritability at 3 months.
  • Magnetic resonance imaging (MRI) to measure amygdala volume at 10 years.
  • Longitudinal parent and self-rated assessments of internalizing and externalizing behaviors from infancy to adolescence.

Main Results:

  • Infants with excessive crying exhibited higher rates of internalizing and externalizing behaviors throughout childhood.
  • Irritability in infancy showed a similar pattern of association with later behavioral problems.
  • Children with a history of excessive crying had significantly smaller amygdala volumes at 10 years of age.
  • The observed association between early crying/irritability and amygdala volume was consistent.

Conclusions:

  • Excessive crying and irritability in infancy may indicate an early vulnerability to developing behavioral problems.
  • These early behavioral patterns are potentially linked to neurobiological differences, specifically in amygdala development.
  • Findings highlight the importance of considering infant behavior as a potential early marker for later mental health and neurodevelopmental outcomes.