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Symptom patterns and life with post-acute COVID-19 in children aged 8-17 years: a mixed-methods study protocol

Alice Faux-Nightingale1, Claire Burton2, Helen Twohig2

  • 1School of Medicine, Keele University, Keele, Newcastle, UK a.faux-nightingale@keele.ac.uk.

BJGP Open
|February 9, 2023
PubMed

Insights

This study investigates long-COVID in children and young people (CYP), examining symptoms and needs. Findings will improve understanding and clinical care for pediatric long-COVID patients.

Area of Science:

  • Pediatric Health
  • Infectious Diseases
  • Longitudinal Studies

Background:

  • Limited understanding of long-COVID in children and young people (CYP) despite extensive research on acute COVID-19.
  • Long-COVID is defined as symptoms persisting beyond 4 weeks post-infection.

Purpose of the Study:

  • To characterize the longer-term effects of COVID-19 infection in CYP.
  • To identify the specific needs of CYP experiencing long-COVID.
  • To inform clinical practice and enhance understanding of pediatric long-COVID.

Main Methods:

  • Observational prospective cohort and linked qualitative study in the West Midlands, UK.
  • Online questionnaires for 12-month symptom monitoring in CYP aged 8-17 years.
  • Interviews, diaries for symptomatic CYP, and focus groups with professionals; statistical and thematic analysis.

Main Results:

  • The study aims to describe the incidence, symptom resolution rates, and predictors of long-COVID in CYP.
  • Qualitative data will explore the impact of long-COVID on CYP and their families.
  • Statistical models will identify associations between predictors and long-COVID development.

Conclusions:

  • This research will provide a comprehensive description of long-COVID features in CYP.
  • It will elucidate the impact of long-COVID on the lives of CYP and their families.
  • Findings are expected to enhance clinical understanding and inform evidence-based practice for pediatric long-COVID.
Abstract

Keywords:
COVID-19child healthlong-COVIDprimary health caresymptom patterns

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