Related Experiment Video

Updated: Aug 11, 2025

CIRCLE-Seq for Interrogation of Off-Target Gene Editing
08:23

CIRCLE-Seq for Interrogation of Off-Target Gene Editing

Published on: November 1, 2024

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The PROTECTOR strategy employs dCas orthologs to sterically shield off-target sites from CRISPR/Cas activity

Daniel M Sapozhnikov1, Moshe Szyf2

  • 1Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada. daniel.sapozhnikov@mail.mcgill.ca.

Scientific Reports
|February 9, 2023
PubMed

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