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Updated: Aug 11, 2025

Monitoring Stub1-Mediated Pexophagy
Published on: May 12, 2023
Pexophagy in plants: a mechanism to remit cells from oxidative damage caused under high-intensity light
Shino Goto-Yamada1, Kazusato Oikawa2, Yasuko Hayashi3
1Malopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland.
Abstract:
Light is essential for plant growth, but excessive light energy produces reactive oxygen species (ROS), which can seriously damage cells. Mutants defective in ATG (autophagy related) genes show light intensity-dependent leaf damage and ROS accumulation. We found that autophagy is one of the crucial systems in protecting plants from ROS-induced damage by removing oxidative peroxisomes. Damaged peroxisomes are targeted by the PtdIns3P marker and specifically engulfed by phagophores labeled by ATG18a-GFP. Under high-intensity light, huge peroxisome aggregates are induced and captured by vacuolar membranes. Research provides a deeper understanding of plant stress response to light irradiation.
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