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Left atrial appendage occlusion.

David R Holmes1, Kasper Korsholm2, Josep Rodés-Cabau3

  • 1Department of Cardiology, Mayo Clinic School of Medicine, Rochester, MN, USA.

Eurointervention : Journal of Europcr in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
|February 10, 2023
PubMed
Summary
This summary is machine-generated.

Left atrial appendage occlusion (LAAO) offers a new stroke prevention strategy for patients with non-valvular atrial fibrillation (NVAF). This review covers LAAO

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Area of Science:

  • Cardiology
  • Neurology
  • Medical Devices

Background:

  • Stroke prevention is a major health priority, with identified high-risk patient groups.
  • Established interventions include anticoagulation for atrial fibrillation and revascularization for carotid disease.
  • Left atrial appendage occlusion (LAAO) is an emerging option for specific non-valvular atrial fibrillation (NVAF) patients.

Approach:

  • This review focuses on LAAO for NVAF patients.
  • It examines the pathophysiology, patient selection, and procedural aspects of LAAO.
  • Outcomes, adjunctive therapies, complications, and long-term results are evaluated.

Key Points:

  • LAAO is a percutaneous procedure targeting the left atrial appendage to prevent stroke.
  • Patient selection is crucial for successful LAAO outcomes.
  • The review synthesizes current evidence on LAAO efficacy and safety.

Conclusions:

  • LAAO represents a significant advancement in stroke prevention for NVAF.
  • Understanding LAAO's role, risks, and benefits is essential for clinical practice.
  • Further research will refine LAAO indications and optimize patient management.