Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Goodpasture's syndrome].

V Herout, Z Nozicka, J Erben

    Ceskoslovenska Patologie
    |November 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    This study details four cases of Goodpasture's syndrome, a rare autoimmune disease affecting the lungs and kidneys. Findings highlight specific histopathological and immunohistological markers crucial for diagnosing this severe condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The combination of nanofibrous and microfibrous materials for enhancement of cell infiltration and in vivo bone tissue formation.

    Biomedical materials (Bristol, England)·2017
    Same author

    [Multiple Non-ossifying Fibroma (Case-report).].

    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2010
    Same author

    In vitro and in vivo antioxidant activity of ambroxol.

    Clinical and experimental medicine·2004
    Same author

    [Nodular faciitis--rare localization on the eye (a case report)].

    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti·2004
    Same author

    [C-reactive protein in diagnosis of complications in renal insufficiency and failure].

    Vnitrni lekarstvi·2004
    Same author

    [IgA nephropathy, isolated hematuria and renal biopsy].

    Vnitrni lekarstvi·2003
    Same journal

    EBV-associated plasmacytic variant of Castleman disease: more than a decade-long diagnostic odyssey - a case report.

    Ceskoslovenska patologie·2026
    Same journal

    Castleman-Like Lymphadenopathy in a Patient with Mixed Connective Tissue Disease: A Case Report and Review of the Literature.

    Ceskoslovenska patologie·2026
    Same journal

    Targeted gene expression profiling as a tool for diagnostic cell-of-origin determination and prognostic stratification in diffuse large B-cell lymphoma.

    Ceskoslovenska patologie·2026
    Same journal

    The advantages and limitations of the new FIGO 2023 staging system for endometrial carcinoma from the perspective of the clinician and pathologist.

    Ceskoslovenska patologie·2026
    Same journal

    Castleman disease - one name, many faces.

    Ceskoslovenska patologie·2026
    Same journal

    Testing Claudin 18.2 Expression in Gastric and Gastroesophageal Junction Adenocarcinoma: Current Status and Near‑Future Outlook.

    Ceskoslovenska patologie·2026
    See all related articles

    Area of Science:

    • Nephrology
    • Pulmonology
    • Immunopathology

    Background:

    • Goodpasture's syndrome is a rare autoimmune disorder characterized by pulmonary hemorrhage and glomerulonephritis.
    • Early diagnosis and understanding of its pathogenesis are critical for patient outcomes.

    Observation:

    • The study presents four cases (2 males, 2 females; ages 18-65) of Goodpasture's syndrome.
    • Clinical course, histopathology, and immunohistology were examined in detail for each case.

    Findings:

    • Histopathology revealed pulmonary hemorrhage, acute alveolitis, and acute/subacute glomerulonephritis.
    • Scarce multinucleated cells in renal lesions are considered diagnostically valuable, suggesting antibody interaction with basement membranes.
    • Immunohistology demonstrated linear fluorescence along alveolar septa basement membranes in all cases, and in glomerular capillary walls in three.

    Related Experiment Videos

    Implications:

    • Findings underscore the diagnostic significance of multinucleated cells and linear basement membrane fluorescence in Goodpasture's syndrome.
    • One case showed granular fluorescence, indicating immune complex participation in pathogenesis, suggesting potential variations in disease mechanisms.