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Published on: December 6, 2016
Adherence to Continuous Positive Airway Pressure Therapy in Pediatric Patients with Obstructive Sleep Apnea: A
Bundit Sawunyavisuth1, Chetta Ngamjarus2, Kittisak Sawanyawisuth3
1Department of Marketing, Faculty of Business Administration and Accountancy, Khon Kaen University, Khon Kaen, Thailand.
Insights
Children with obstructive sleep apnea (OSA) show a 46.56% adherence rate to continuous positive airway pressure (CPAP) therapy. Factors like younger age, lower BMI, and higher apnea-hypopnea index (AHI) are linked to better CPAP adherence.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Public Health
Background:
- Obstructive sleep apnea (OSA) is a significant health concern in children.
- Continuous positive airway pressure (CPAP) is an effective treatment for pediatric OSA.
- CPAP adherence rates in children are highly variable.
Purpose of the Study:
- To systematically review and evaluate CPAP adherence rates in children with OSA.
- To identify factors associated with CPAP adherence in pediatric OSA patients.
Main Methods:
- Systematic review of observational studies using objective CPAP adherence evaluation.
- Literature search across four major databases.
- Meta-analysis employing a fixed-effect model.
Main Results:
- Included 34 studies with 21,737 pediatric patients.
- Average CPAP adherence rate was 46.56%.
- Younger age, lower body mass index (BMI), and higher apnea-hypopnea index (AHI) were associated with better adherence.
Conclusions:
- Pediatric OSA patients exhibit a 46.56% CPAP adherence rate.
- Younger age, lower BMI, and higher AHI are key predictors of acceptable CPAP adherence.
- Understanding these factors can help improve treatment outcomes for children with OSA.
Introduction:
Obstructive sleep apnea (OSA) is a public health problem that affects children. Although continuous positive airway pressure (CPAP) therapy is effective, the CPAP adherence rate in children is varied. This study aimed to evaluate the CPAP adherence rate and factors associated with CPAP adherence in children with OSA using a systematic review.
Methods:
The inclusion criteria were observational studies conducted in children with OSA and assessed adherence of CPAP using objective evaluation. The literature search was performed in four databases. Meta-analysis using fixed-effect model was conducted to combine results among included studies.
Results:
In all, 34 studies that evaluated adherence rate and predictors of CPAP adherence in children with OSA were included, representing 21,737 patients with an average adherence rate of 46.56%. There were 11 calculations of factors predictive of CPAP adherence: age, sex, ethnicity, body mass index, obesity, income, sleep efficiency, the apnea-hypopnea index (AHI), severity of OSA, residual AHI, and lowest oxygen saturation level. Three different factors were linked to children with adherence and non-adherence to CPAP: age, body mass index, and AHI.
Conclusion:
The CPAP adherence rate in children with OSA was 46.56%. Young age, low body mass index, and high AHI were associated with acceptable CPAP adherence in children with OSA.
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