[Heart failure with preserved ejection fraction (HFpEF) : Diagnosis and treatment]

Heart failure with preserved ejection fraction (HFpEF) accounts for around half of all hospitalizations associated with heart failure. The prevalence of HFpEF is increasing, mainly due to an aging population and a growing burden of comorbidities, such as hypertension, diabetes, and obesity. Despite increased research efforts, there are still important gaps in terms of the pathophysiological understanding of HFpEF and the practice-related diagnostics. As HFpEF may also be due to rare cardiac diseases, in unclear constellations patients should be referred at an early stage to specialized centers for diagnostics and treatment to facilitate best clinical care. Only recently, evidence has emerged that innovative pharmacological approaches are also able to reduce hard clinical endpoints in HFpEF. These strategies now await implementation into routine care.