Related Experiment Video

Updated: Aug 10, 2025

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
08:04

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function

Published on: February 27, 2019

11.8K

Plasticity of lineage switch in B-ALL allows for successful rechallenge with CD19-directed immunotherapy

Brittany M Lee1,2, Corinne Summers2,3, Karen M Chisholm4,5

  • 1Seattle Children's Research Institute, Seattle, WA.

Blood Advances
|February 10, 2023
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells
09:49

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells

Published on: August 13, 2010

19.2K
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

14.8K

Related Experiment Videos

Last Updated: Aug 10, 2025

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
08:04

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function

Published on: February 27, 2019

11.8K
Induction and Assessment of Class Switch Recombination in Purified Murine B Cells
09:49

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells

Published on: August 13, 2010

19.2K
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

14.8K

Related Concept Videos

Lineage Commitment01:21

Lineage Commitment

3.0K
Commitment is the  process whereby stem cells:
3.0K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

2.1K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
2.1K
B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

2.9K
The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
2.9K

Articles linked to this work by shared authors, journal, and citation graph.

Intracerebroventricular B7-H3-targeting CAR T cells for non-pontine DMG and recurrent/refractory pediatric CNS tumors: a phase 1 trial.

Neuro-oncology·2026

AAML1831: A Phase III Trial Comparing Standard Induction Therapy With CPX-351 in De Novo Pediatric AML: A Report From the Children's Oncology Group.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026

Plasticity under pressure: biology and detection of lineage switch in acute leukemia.

Leukemia·2026

Chimeric Antigen Receptor T-Cell Therapy in Autoimmune Disorders: An Expert Panel Opinion From the American Society for Transplantation and Cellular Therapy.

Transplantation and cellular therapy·2026

Clinical implications of RAS mutations in AML: prognostic significance is based upon the involved gene and mutation complexity.

Blood advances·2026

X-linked SEPTIN6-related congenital neutropenia and B cell deficiency.

Journal of human immunity·2026

Diagnostic Accuracy of Fat Pad Sampling and Bone Marrow Biopsy for AL Amyloidosis: A Systematic Review and Meta-Analysis.

Blood advances·2026

Unfolded protein response signaling promotes myeloid cell production and cooperates with oncogenic mutation.

Blood advances·2026

PhenX Toolkit Measurement Protocols for Sickle Cell Disease Pain.

Blood advances·2026

Murine model for Congenital Dyserythropoietic Anemia Type I.

Blood advances·2026

Mast cells enhance venous thrombus stability and lung fibrin deposition in murine sepsis.

Blood advances·2026

Teclistamab and Daratumumab Immune-Based Doublet Therapy for Relapsed/Refractory Multiple Myeloma: the TRIMM-2 Study.

Blood advances·2026

Real-world outcomes of CD34⁺ mobilization and early autologous hematopoietic stem cell transplantation recovery after daratumumab-based induction.

Hematology, transfusion and cell therapy·2026

Complete Remission to Imatinib in a Myeloid Neoplasm with Basophilia and PRKG2::PDGFRA Gene Fusion: A Case Report.

Acta haematologica·2026

Effect of JAK inhibitors on extraintestinal manifestations and concurrent immune-mediated inflammatory diseases in patients with inflammatory bowel disease.

Journal of Crohn's & colitis·2026

Durable CNS remission with elranatamab and intrathecal therapy in relapsed/refractory multiple myeloma.

Annals of hematology·2026

Plasma Cell Selection and Migration in the Establishment of Long-Lived Antibody Responses.

Immunological reviews·2026

The "Lost" and "Found" IUD: a case of concurrent intrauterine and intraperitoneal devices with delayed recognition.

International journal of surgery case reports·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us