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Cell Type-specific Gene Expression Profiling in the Mouse Liver
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Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic

Josepmaria Argemi1,2, Maria U Latasa3, Stephen R Atkinson4

  • 1Division of Gastroenterology, Hepatology and Nutrition, Pittsburgh Liver Research Center, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, 15261, USA.

Nature Communications
|February 10, 2023
PubMed
Abstract

No abstract available in PubMed .

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
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