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Related Concept Videos

What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
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The Relationship between Cancer and Dementia: An Updated Review.

Yung-Shuo Kao1, Cheng-Chang Yeh2, Yi-Fang Chen3

  • 1Dr Kao Clinic, Taichung 406, Taiwan.

Cancers
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PubMed
Summary

Cancer treatments may affect cognitive function, increasing dementia risk in older adults. Research explores these links to improve prevention and early detection for better patient outcomes.

Keywords:
cancercancer treatmentcognitive impairmentdementia

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Area of Science:

  • Geriatric Oncology
  • Neuro-oncology
  • Cognitive Neurology

Background:

  • Cancer and dementia risks rise with age, posing treatment dilemmas for older patients.
  • Emerging research suggests a link between cancer and dementia, but mechanisms are unclear.
  • Cognitive effects of cancer therapies are increasingly understood.

Purpose of the Study:

  • To review the incidence and mechanisms of cognitive impairment in various cancer patients undergoing therapy.
  • To explore potential risk factors for early cognitive changes in cancer patients.
  • To provide insights into the pathophysiology of dementia in the context of cancer.

Main Methods:

  • Literature review of current research on cancer-associated cognitive impairment.
  • Summary of studies on lung, breast, head and neck, gastric, prostate, colorectal, and brain cancers.
  • Analysis of cognitive effects across different cancer therapies.

Main Results:

  • Cognitive impairment is a recognized effect of cancer and its treatments.
  • Specific cancer types and therapies are associated with varying degrees of cognitive decline.
  • Potential risk factors for cognitive changes are being identified.

Conclusions:

  • Understanding cancer-related cognitive impairment is crucial for clinical practice.
  • Developing prevention methods and early screening for cognitive changes is needed.
  • Therapeutic strategies to preserve cognitive function before cancer treatment show promise.