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Updated: Aug 18, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
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Published on: March 8, 2015

Outcome in bipolar affective disorder after stereotactic tractotomy

L M Lovett1, D M Shaw

  • 1Department of Psychological Medicine, University of Wales College of Medicine, Whitchurch Hospital, Cardiff.

The British Journal of Psychiatry : the Journal of Mental Science
|July 1, 1987
PubMed

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Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...