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Classification of Retinal Diseases in Optical Coherence Tomography Images Using Artificial Intelligence and Firefly
Mehmet Batuhan Özdaş1, Fatih Uysal2, Fırat Hardalaç1
1Department of Electrical and Electronics Engineering, Faculty of Engineering, Gazi University, Ankara TR 06570, Turkey.
Diagnostics (Basel, Switzerland)
|February 11, 2023
Summary
This study introduces a hybrid system for faster, more accurate biomedical disease diagnosis. Combining machine learning and deep learning, it achieves high accuracy with reduced computational load for retinal diseases.
Area of Science:
- Biomedical engineering
- Medical imaging analysis
- Artificial intelligence in healthcare
Background:
- Automatic diagnosis of biomedical diseases is increasingly reliant on Deep Learning (DL).
- DL offers high accuracy but demands substantial data and computational resources, posing challenges for systems with limited processing power.
- Traditional Machine Learning (ML) is faster and less computationally intensive but generally yields lower accuracy compared to DL.
Purpose of the Study:
- To develop a hybrid system for biomedical disease diagnosis that balances high accuracy with reduced computational load and time.
- To specifically address the diagnosis of retinal diseases using this novel hybrid approach.
Main Methods:
- Image preprocessing for retinal layer extraction.
- Integration of traditional feature extractors with pre-trained Deep Learning feature extractors.
- Utilizing the Firefly algorithm for optimal feature selection.
- Employing multiple binary classifications with Machine Learning classifiers instead of a single multiclass classification.
Main Results:
- The hybrid system achieved a mean accuracy of 0.957 on the first public dataset.
- The system demonstrated a mean accuracy of 0.954 on the second public dataset.
- The developed method effectively reduces computational requirements while maintaining high diagnostic accuracy.
Conclusions:
- The proposed hybrid system offers a promising solution for efficient and accurate biomedical disease diagnosis.
- This approach effectively overcomes the limitations of using solely Deep Learning or traditional Machine Learning for such tasks.
- The method shows significant potential for clinical application in diagnosing retinal diseases and potentially other biomedical conditions.

