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Updated: Aug 10, 2025

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Application of Vibrational Spectroscopic Techniques in the Study of the Natural Polysaccharides and Their
Barbara Gieroba1, Grzegorz Kalisz1, Mikolaj Krysa1
1Independent Unit of Spectroscopy and Chemical Imaging, Medical University of Lublin, Chodźki 4a Street, 20-093 Lublin, Poland.
Abstract:
Polysaccharides are one of the most abundant natural polymers and their molecular structure influences many crucial characteristics-inter alia hydrophobicity, mechanical, and physicochemical properties. Vibrational spectroscopic techniques, such as infrared (IR) and Raman spectroscopies are excellent tools to study their arrangement during polymerization and cross-linking processes. This review paper summarizes the application of the above-mentioned analytical methods to track the structure of natural polysaccharides, such as cellulose, hemicellulose, glucan, starch, chitosan, dextran, and their derivatives, which affects their industrial and medical use.
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