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Updated: Aug 10, 2025

Effect of Artificial Tear Formulations on the Metabolic Activity of Human Corneal Epithelial Cells after Exposure to Desiccation
Published on: May 2, 2020
A Critical Appraisal of the Physicochemical Properties and Biological Effects of Artificial Tear Ingredients and
Judy Weng1, Michael K Fink2, Ajay Sharma1
1Chapman University School of Pharmacy, Chapman University, Irvine, CA 92618, USA.
Abstract:
Dry eye disease is among the most prevalent diseases affecting the ocular surface. Artificial tears remain the cornerstone therapy for its management. There are currently a wide variety of marketed artificial tears available to choose from. These artificial tears differ significantly in their composition and formulation. This article reviews the physicochemical and biological properties of artificial tear components and how these characteristics determine their use and efficacy in the management of dry eye. Furthermore, this article also discusses the various formulations of artificial tears such as macro and nanoemulsion and the type of preservatives present in them.
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