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Types of Step-Growth Polymers: Polyesters01:20

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The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the...
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Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
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Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
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Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
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Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
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Overview of Antimicrobial Biodegradable Polyester-Based Formulations.

Oana Gherasim1, Valentina Grumezescu1,2, Stefan Andrei Irimiciuc1,2

  • 1National Institute for Lasers, Plasma and Radiation Physics, 077125 Magurele, Romania.

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|February 11, 2023
PubMed
Summary

Biopolymers offer advanced antimicrobial solutions beyond conventional therapies, addressing drug resistance and infection complications. Their versatile properties enable novel antimicrobial formulations and devices for enhanced efficacy and targeted delivery.

Keywords:
anti-infective therapypoly(3-hydroxybutyrate-co-3-hydroxyvalerate)poly(lactide-co-glycolide)polycaprolactonepolylactide

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Antimicrobial Technology

Background:

  • Conventional anti-infective therapies are insufficient due to drug resistance and pathogen adaptability.
  • Life-threatening microbial infections necessitate advanced antimicrobial strategies and devices.
  • Biopolymers present a promising avenue for developing novel antimicrobial agents and materials.

Purpose of the Study:

  • To review antimicrobial polyester-based formulations.
  • To explore the impact of material dimensionality on antimicrobial properties.
  • To analyze the influence of production and post-processing methods on efficacy.

Main Methods:

  • Review of existing literature on biopolymer-based antimicrobial formulations.
  • Analysis of polyester-based materials for antimicrobial applications.
  • Evaluation of structure-property relationships, including dimensionality and processing.

Main Results:

  • Biopolymers offer tunable properties like biocompatibility, degradability, and functionalization for antimicrobial applications.
  • Polyester-based materials can be fabricated into various forms (particles, fibers, films, scaffolds) for diverse uses.
  • Material dimensionality and processing routes significantly affect the performance of antimicrobial formulations.

Conclusions:

  • Biopolymers are versatile platforms for creating effective antimicrobial formulations and devices.
  • Tailoring material properties through processing and structural design is crucial for optimizing antimicrobial efficacy.
  • Advanced biopolymer-based strategies are essential for combating challenging microbial infections.