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Immunonutrition in Orthopedic and Traumatic Patients
Pietro Gregori1, Edoardo Franceschetti1, Susanna Basciani1
1Department of Orthopedic and Trauma Surgery, Campus Bio-Medico University, 00128 Rome, Italy.
Immunonutrition, or immune-enhancing nutrition, shows positive clinical outcomes for orthopedic and trauma surgery patients. Further research is needed to fully understand its effects and applications in these surgical fields.
Area of Science:
- Surgical Nutrition
- Immunology
- Orthopedic Surgery
Background:
- Nutrition intervention is evolving in surgical settings.
- Immunonutrition is recognized for reducing complications in surgical oncology.
- Limited research exists on immunonutrition in orthopedics.
Purpose of the Study:
- To review the current application of immune-enhanced compounds in orthopedic and trauma surgical patients.
- To summarize the state of the art in immunonutrition for surgical, orthopedic, and traumatic conditions.
Main Methods:
- Systematic review following PRISMA guidelines.
- Comprehensive literature search of PubMed, EMBASE, and Cochrane Library.
- Inclusion of eight studies (six trauma, two elective orthopedic surgery).
Main Results:
- A positive impact of immunonutrition was observed in orthopedic and trauma surgical settings.
- All analyzed studies indicated favorable clinical outcomes with immunonutrition diets.
- Data were analyzed using R software.
Conclusions:
- Current literature suggests a beneficial effect of immunonutrition in orthopedic and trauma surgery.
- More extensive randomized controlled trials are necessary to investigate its full effects and applications.
- Further research should critically examine immunonutrition's role in orthopedic and traumatic fields.
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