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Updated: Aug 10, 2025

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Published on: May 5, 2023
Theofilos Karasavvidis1, Cale A Pagan Moldenhauer1, Fares S Haddad2
1Adult Reconstruction and Joint Replacement Service, Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York.
Surgeons are moving beyond traditional neutral mechanical alignment (MA) in total knee arthroplasty (TKA) towards individualized techniques for better patient outcomes. This shift requires understanding knee phenotypes and a cautious, stepwise approach to implementation.
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