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Updated: Aug 10, 2025

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Evaluation of right atrial function by two-dimensional echocardiography and strain imaging in patients with RCA CTO
Recha Blessing1,2, Ioannis Drosos3, Thomas Münzel4,5
1University Medical Center Mainz - Center of Cardiology, Johannes Gutenberg University, Mainz, Germany. recha.blessing@unimedizin-mainz.de.
Insights
Successful recanalization of chronic total occlusion in the right coronary artery (RCA CTO) significantly improves right atrial (RA) function. This study highlights the benefits of restoring blood flow for right heart health.
Area of Science:
- Cardiology
- Vascular Medicine
- Echocardiography
Background:
- The right coronary artery (RCA) supplies blood to the right heart.
- The impact of RCA chronic total occlusion (CTO) on right heart function and the benefits of revascularization are not well understood.
Purpose of the Study:
- To evaluate changes in right atrial (RA) function after successful RCA CTO recanalization.
- To assess the efficacy of restoring blood flow on right heart performance.
Main Methods:
- Fifty-five patients with RCA CTO underwent successful recanalization.
- Right atrial strain imaging was performed before and 6 months after the procedure.
- Transthoracic echocardiography was used to assess RA function.
Main Results:
- No significant differences were observed in RA volume, area, or dimensions post-recanalization.
- Mean RA reservoir strain significantly improved from baseline (30.9%) to follow-up (33.4%) (p < 0.001).
- Mean RA contraction strain also showed significant improvement (p < 0.001).
Conclusions:
- Right atrial function is impaired in patients with RCA CTO.
- Successful revascularization of RCA CTO leads to significant improvements in RA function, as evidenced by strain imaging.
Objectives:
The right heart is mainly supplied with blood by the right coronary artery (RCA). The impact of RCA chronic total occlusion (CTO) on the function of the right heart [right atrium (RA) and ventricle (RV)] and whether successful recanalization of a RCA CTO improves the function of the right heart is not clearly understood yet. We aimed to evaluate right atrial function after recanalization of the RCA using transthoracic echocardiography with additional strain imaging.
Methods And Results:
Fifty-five patients undergoing RCA CTO recanalization at the University Medical Center of Mainz were included in the study. Right atrial strain was assessed before and 6 months after successful CTO revascularization. The median age of the total collective was 66 (50-90) years. We did not find difference in our analysis of RA Volume (p 0.086), RA area (p 0.093), RA major dimension (p 0.32) and RA minor dimension (p 0.139) at baseline and follow-up. Mean RA reservoir strain at baseline was 30.9% (21.1-43.0) vs. 33.4% (20.7-47.7) at follow up (p < 0.001). Mean RA conduit strain was - 17.5% (- 10.7-(- 29.7)) at baseline vs. - 18.2% (- 9.6-(- 31.7)) at follow-up (p = 0.346). Mean RA contraction strain was - 12.9% (- 8.0- (- 21.3)) at baseline vs. - 15.5% (- 8.7-(- 26.6)) at follow-up (p < 0.001).
Conclusion:
Right atrial function was altered in patients with RCA CTO. Successful revascularisation of an RCA CTO improved RA function assessed by strain imaging at follow-up.
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