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Astaxanthin production using Paracoccus carotinifaciens: a way forward?
Cassamo U Mussagy1, Jorge F B Pereira2, Laurent Dufossé3
1Escuela de Agronomía, Facultad de Ciencias Agronómicas y de los Alimentos, Pontificia Universidad Católica de Valparaíso, Quillota 2260000, Chile.
Trends in Biotechnology
|February 12, 2023
Summary
Paracoccus carotinifaciens is a promising microbe for producing natural astaxanthin (AXT) in sustainable biorefineries. Its rapid growth, high yields, and unique cell wall structure offer significant advantages for bioeconomy applications.
Area of Science:
- Microbiology
- Biotechnology
- Sustainable Chemistry
Background:
- Microbial production of natural compounds is crucial for bioeconomy development.
- Astaxanthin (AXT) is a high-value carotenoid with significant health benefits.
- Paracoccus carotinifaciens is known for its potential in producing natural products.
Purpose of the Study:
- To highlight Paracoccus carotinifaciens as a key microbial factory for astaxanthin (AXT) production.
- To emphasize the advantages of using this bacterium for sustainable biorefineries.
- To underscore its contribution to the bioeconomy.
Main Methods:
- Cultivation of Paracoccus carotinifaciens.
- Analysis of production titers.
- Evaluation of cell wall characteristics.
Main Results:
- Paracoccus carotinifaciens demonstrates potential as a microbial factory for natural astaxanthin (AXT).
- Short cultivation times and high production titers were observed.
- The bacterium possesses a thin cell wall, advantageous for extraction and processing.
Conclusions:
- Paracoccus carotinifaciens is a promising candidate for sustainable third-generation biorefineries.
- Its unique characteristics support efficient and cost-effective astaxanthin production.
- This bacterium contributes to the development of a healthier, bio-based economy.

