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In vitro activity in deptomycin (LY-146032) compared with other antimicrobial agents against gram-positive cocci
D N Wright1, B Saxon, J M Matsen
1Department of Pathology, University of Utah School of Medicine, Salt Lake City.
Diagnostic Microbiology and Infectious Disease
|August 1, 1987
Abstract:
A comparison was made of the activity of deptomycin (LY-146032) with that of ampicillin, cephalexin, cefamandole, cephalothin, erythromycin, teicoplanin, tetracycline, and vancomycin. The minimal inhibitory concentration (MICs) for greater than or equal to 90% of 356 Gram-positive cocci, against deptomycin, were less than or equal to 2 micrograms/ml. The MICs for the other antimicrobials varied greatly depending on the compound. A slight and unexplained inoculum effect was observed for LY-146032.