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Updated: Aug 10, 2025

Quantification of Hypopigmentation Activity In Vitro
Published on: March 6, 2019
Diffuse Hypopigmented Keratoses: An Under-Reported and Often Misdiagnosed Entity
Roja Renuka Sane1, K Manoharan1, G Sukanya1
1Department of Dermatology Venereology and Leprosy, Sree Balaji Medical College and Hospital, Chrompet, Chennai, Tamil Nadu, India.
Abstract:
The appearance of widely diffuse hypopigmented keratotic lesions has been linked to a number of dermatological conditions like pityriasis versicolor, stucco keratoses, confetti leukoderma, and guttate leukoderma of Darier's disease. Specific clinical and histologic characteristics distinguish them from one another. One of the differentials for diffuse hypopigmented keratotic lesions has been a novel entity called disseminated hypopigmented keratoses (DHK). We are hereby highlighting the importance of bedside investigations like potassium hydroxide wet mount and dermatoscopy in ruling out such misleading dermatological conditions. It looks to be benign and slowly progressing, albeit not linked to any systemic symptoms. We hereby present a case of diffuse hypopigmented keratoses with no proven underlying cause.
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