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Is sesamol present in sesame oil?
R Hayakawa1, K Matsunaga, M Suzuki
1Division of Dermatology, Nagoya University Branch Hospital, Japan.
Contact Dermatitis
|September 1, 1987
Summary
Sesame oil contains allergens sesamolin and sesamin, which can cause cheilitis. Analysis confirmed these allergens in sesame oil, but not sesamol, highlighting specific contact dermatitis triggers.
Area of Science:
- Dermatology
- Allergology
- Analytical Chemistry
Background:
- Sesame oil is recognized for containing potential contact allergens, including sesamolin, sesamin, and sesamol.
- Contact dermatitis is a common adverse reaction to various cosmetic ingredients.
Observation:
- A patient presented with cheilitis, a form of dermatitis affecting the lips.
- The cheilitis was attributed to the presence of sesame oil in a lipstick formulation.
- The patient exhibited allergic reactions specifically to sesamolin and sesamin, but not to sesamol.
Findings:
- High-performance liquid chromatography (HPLC) was employed to analyze the composition of the sesame oil.
- The analysis successfully detected the presence of sesamolin and sesamin within the sesame oil.
- Sesamol was notably absent in the analyzed sesame oil sample.
Implications:
- This study identifies sesamolin and sesamin as key allergens in sesame oil responsible for contact cheilitis.
- The findings aid in diagnosing and managing sesame oil-induced allergic reactions in cosmetics.
- Understanding the specific allergenic components of sesame oil is crucial for product formulation and consumer safety.