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Related Experiment Videos

Sensitivity to sunscreens.

J S English1, I R White, E Cronin

  • 1St John's Hospital for Diseases of the Skin, London, England.

Contact Dermatitis
|September 1, 1987
PubMed
Summary
This summary is machine-generated.

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Sunscreen allergies are uncommon, affecting 5% of patients. Hydroxy methoxy methyl benzophenone was the most frequent contact allergen, with some patients reacting to multiple sunscreen agents.

Area of Science:

  • Dermatology
  • Allergology
  • Photodermatology

Background:

  • Contact dermatitis to sunscreen agents can be a significant clinical issue.
  • Identifying specific allergens is crucial for patient management and product formulation.

Purpose of the Study:

  • To review patients sensitized to sunscreen agents attending a Contact Dermatitis Clinic.
  • To identify the specific sunscreen agents causing allergic reactions and photopatch test positivity.

Main Methods:

  • Retrospective review of 280 patients tested with sunscreens between February 1985 and March 1987.
  • Analysis of positive patch test reactions and photopatch test results to identify causative sunscreen agents.

Main Results:

  • 15 (5%) of 280 patients showed positive reactions to sunscreen agents.

Related Experiment Videos

  • Hydroxy methoxy methyl benzophenone (Mexenone) was the most frequent contact allergen (6 cases).
  • Other identified allergens included isopropyl dibenzoylmethane, octyl dimethyl para-aminobenzoate, butyl methoxy dibenzoylmethane, amyl dimethyl para-aminobenzoate, and ethoxy ethyl-p-methoxy cinnamate.

    • Conclusions:

    • Hydroxy methoxy methyl benzophenone is a significant contact allergen in sunscreens.
    • Several other sunscreen ingredients can cause allergic contact dermatitis and photoallergic reactions.
    • Photopatch testing is valuable for diagnosing photoallergic reactions to sunscreen agents.