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Acute limb ischemia secondary to vaccine-induced thrombotic thrombocytopenia

Bowen Xie1, Dana B Semaan1, Natalie D Sridharan1

  • 1Division of Vascular Surgery, UPMC, Pittsburgh, PA.

Annals of Vascular Surgery. Brief Reports and Innovations
|February 13, 2023
PubMed

Vaccine-associated thrombosis has previously been described in patients presenting with cerebral sinus thrombosis, deep venous thrombosis/pulmonary embolism, or mesenteric venous thrombosis. Only recently has arterial thrombosis gained attention. A new entity known as vaccine-induced thrombotic thrombocytopenia (VITT) has been associated with the coronavirus disease of 2019 (COVID-19) vaccines produced by AstraZeneca and Johnson & Johnson. We describe a case series of three patients who presented with acute limb ischemia with vaccine-associated arterial occlusions, one of whom was diagnosed with VITT.

Keywords:
Acute limb ischemia (ALI)Vaccine-induced thrombotic thrombocytopenia (VITT)

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