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Otosyphilis.

Lucy S Witt1, A Wendy Fujita1, Jeanne Ho2

  • 1Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Open Forum Infectious Diseases
|February 13, 2023
PubMed
Summary
This summary is machine-generated.

Otosyphilis, a syphilis infection of the inner ear, can cause permanent hearing loss. Early diagnosis and treatment are crucial, especially in patients with human immunodeficiency virus (HIV) coinfection.

Keywords:
HIVotosyphilissyphilis

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Area of Science:

  • Infectious Diseases
  • Otolaryngology
  • Immunology

Background:

  • Otosyphilis presents diagnostic challenges and can lead to irreversible auditory and vestibular damage.
  • Coinfection with human immunodeficiency virus (HIV) is common due to immunologic interactions, increasing the risk of neurosyphilis.

Purpose of the Study:

  • To present a case of otosyphilis and new HIV diagnosis in an adult male.
  • To educate non-infectious disease clinicians on otosyphilis recognition, diagnosis, and management.
  • To highlight the relationship between HIV and syphilis and the importance of timely disease identification.

Main Methods:

  • Case report presentation.
  • Review of clinical presentation, diagnostic findings, and treatment of otosyphilis in an HIV-positive patient.
  • Discussion of the interplay between syphilis and HIV.

Main Results:

  • A man in his 50s presented with hearing loss and vertigo, subsequently diagnosed with otosyphilis and HIV.
  • The case underscores the potential for otosyphilis to manifest concurrently with a new HIV diagnosis.

Conclusions:

  • Otosyphilis requires prompt recognition and management to prevent irreversible damage.
  • Clinicians should maintain a high index of suspicion for otosyphilis in patients with auditory or vestibular symptoms, particularly those with HIV.
  • Understanding the HIV-syphilis interaction is vital for comprehensive patient care.