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Fingerprinting MINOCA: Unraveling Clues With Quantitative CMR
Saberio Lo Presti1, Brendan L Eck2, Reza Reyaldeen1
1Department of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
JACC. Case Reports
|February 13, 2023
Summary
Myocardial infarction with nonobstructive coronary arteries (MINOCA) can have varied causes. Cardiac magnetic resonance (CMR) imaging effectively diagnoses these conditions, guiding treatment for better patient outcomes.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Myocardial infarction with nonobstructive coronary arteries (MINOCA) presents a diagnostic challenge.
- Understanding the diverse pathophysiologic mechanisms of MINOCA is crucial for effective management.
Observation:
- This case series details two patients with MINOCA exhibiting distinct underlying causes.
- Both patients underwent comprehensive evaluation using cardiac magnetic resonance (CMR) imaging.
Findings:
- CMR imaging, utilizing both conventional parametric mapping and CMR fingerprinting, provided detailed tissue characterization.
- The imaging results were instrumental in identifying the specific etiology of MINOCA in each patient.
Implications:
- Cardiac magnetic resonance (CMR) imaging is a valuable tool for diagnosing the cause of MINOCA.
- Accurate diagnosis via CMR facilitates the selection of appropriate therapeutic strategies for MINOCA patients.
Keywords:
CAD, coronary artery diseaseCMR, cardiac magnetic resonanceECV, extracellular volumeGRASE, gradient and spin echo sequenceLGE, late gadolinium enhancementMI, myocardial infarctionMINOCAMINOCA, myocardial infarction with nonobstructive coronary arteriesOCT, optical coherence tomographycMRF, cardiac magnetic resonance fingerprintcardiac magnetic fingerprintingcardiac magnetic resonance
