Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

5.4K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.4K
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

76
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
76

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum: "Thermal and chemical control of emission and excited-state dynamics in non-(TMS)3P-derived InP quantum dots" [J. Chem. Phys. 164, 144702 (2026)].

The Journal of chemical physics·2026
Same author

Retrospective case-control study of pre-diagnosis observational and prescription data in Parkinson's disease.

Scientific reports·2026
Same author

Airway segmentation on CT - A systematic review of machine learning tools.

European journal of radiology open·2026
Same author

Longitudinal <sup>1</sup>H and <sup>129</sup>Xe Lung MRI in Patients With Post-COVID Residual Lung Abnormalities.

Journal of magnetic resonance imaging : JMRI·2026
Same author

The Emerging Role of Glucagon-like Peptide 1 (GLP-1)-Based Medications in the Treatment of Heart Failure, with a Focus on Heart Failure with Preserved or Mildly Reduced Ejection Fraction.

Medicina (Kaunas, Lithuania)·2026
Same author

Cardiovascular magnetic resonance in contemporary guidelines: divergence between ESC and NICE across major cardiovascular diseases.

European heart journal. Imaging methods and practice·2026

Related Experiment Video

Updated: Aug 10, 2025

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
11:13

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

Published on: May 24, 2021

6.5K

Quantifying Myocardial Blood Flow and Resistance Using 4D-Flow Cardiac Magnetic Resonance Imaging.

Rebecca C Gosling1,2,3, Gareth Williams1, Abdulaziz Al Baraikan1

  • 1Department of Infection Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.

Cardiology Research and Practice
|February 13, 2023
PubMed
Summary

Quantifying myocardial blood flow (MBF) using 4D flow cardiac magnetic resonance (CMR) is feasible. Reduced MBF was observed in patients with myocardial infarction (MI) and microvascular obstruction (MVO).

More Related Videos

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

3.4K
Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation
06:56

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Published on: January 7, 2021

2.5K

Related Experiment Videos

Last Updated: Aug 10, 2025

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
11:13

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

Published on: May 24, 2021

6.5K
In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

3.4K
Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation
06:56

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Published on: January 7, 2021

2.5K

Area of Science:

  • Cardiovascular Imaging
  • Medical Physics
  • Physiology

Background:

  • Coronary microvascular dysfunction is a common cause of ischaemia with nonobstructive coronary arteries, posing diagnostic challenges.
  • Noninvasive myocardial blood flow (MBF) quantification via stress perfusion cardiac magnetic resonance (CMR) or positron emission tomography is limited by practical and technical constraints.
  • Coronary sinus (CS) flow quantification using 4D flow CMR presents a potentially simpler method for MBF assessment.

Purpose of the Study:

  • To evaluate the feasibility of quantifying myocardial blood flow (MBF) using 4D flow cardiac magnetic resonance (CMR).
  • To assess MBF and myocardial resistance (MyoR) in healthy volunteers and patients with acute myocardial infarction (MI), with and without microvascular obstruction (MVO).

Main Methods:

  • Cardiac magnetic resonance (CMR) imaging was performed on 30 subjects (10 healthy volunteers, 10 MI without MVO, 10 MI with MVO).
  • Coronary sinus (CS) contours were traced, and flow was quantified using 4D flow CMR.
  • Myocardial blood flow (MBF) and myocardial resistance (MyoR) were calculated and normalized for myocardial mass.

Main Results:

  • Myocardial blood flow (MBF) was successfully quantified in all subjects.
  • MBF was significantly lower in patients with MI (85.7 ± 30.5 mL/min) and MI with MVO (67.9 ± 29.2 mL/min) compared to healthy controls (123.8 ± 48.4 mL/min).
  • Myocardial resistance (MyoR) was elevated in patients with MI and further increased in those with MI and MVO.

Conclusions:

  • 4D flow CMR enables quantification of myocardial blood flow (MBF) and myocardial resistance (MyoR).
  • Resting MBF is reduced in patients with myocardial infarction and microvascular obstruction.