Mucormycosis and Aspergillosis Infection Following Maxillofacial Trauma: Case Report

Area of Science:

• Mycology
• Infectious Diseases
• Oral and Maxillofacial Surgery

Background:

• Mucormycosis is an invasive fungal infection caused by Mucoraceae family fungi.
• It typically affects immunocompromised individuals, including those with uncontrolled diabetes, renal failure, or undergoing chemotherapy or steroid therapy.
• Maxillofacial trauma can be a predisposing factor for opportunistic infections.

Purpose of the Study:

• To report a rare case of co-infection with Mucormycosis and Aspergillosis.
• To describe the management of this mixed fungal infection following maxillofacial trauma.
• To emphasize the importance of considering opportunistic infections in trauma patients with underlying risk factors.

Main Methods:

• Literature review of Mucormycosis and Aspergillosis.
• Clinical case presentation of a patient with maxillofacial trauma.
• Diagnosis of mixed fungal infection through laboratory tests and imaging.
• Treatment involving both medical antifungal therapy and surgical intervention.

Main Results:

• A patient with maxillofacial trauma developed a mixed opportunistic fungal infection.
• The infection involved both Mucormycosis and Aspergillosis.
• Successful treatment was achieved through a combination of medical and surgical management.

Conclusions:

• Maxillofacial trauma can predispose patients to rare mixed fungal infections like Mucormycosis and Aspergillosis.
• Prompt and combined medical-surgical intervention is crucial for managing such complex infections.
• Awareness of opportunistic infections in immunocompromised or traumatized patients is essential for timely diagnosis and treatment.