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Updated: Aug 10, 2025

Author Spotlight: Unveiling the Role of SNF2L in Replication Fork Stability and Genome Duplication
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Published on: August 23, 2024

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The Cancer Testes Antigen, HORMAD1, is a Tumor-Specific Replication Fork Protection Factor

Luis Reza Herrera, Kathleen McGlynn, Zane A Gibbs

    Biorxiv : the Preprint Server for Biology
    |February 13, 2023
    PubMed
    Summary

    HORMAD1 protects lung adenocarcinoma cells from DNA replication stress by preventing nascent DNA degradation and maintaining genomic integrity. Its loss leads to increased DNA damage and chromosomal aberrations.

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