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Updated: Aug 10, 2025

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
Published on: December 29, 2015
Prevalence and genetic diversity in bovine parechovirus infecting Japanese cattle
Mami Oba1,2, Shiho Obinata2, Hitoshi Takemae1
1Center for infectious Disease Epidemiology and Prevention Research, Tokyo University of Agriculture and Technology, 183-8509, Fuchu, Tokyo, Japan.
Abstract:
The first bovine parechovirus (Bo_ParV) was reported in 2021, and currently, only two nearly complete genome sequences of Bo_ParV are available. In this study, we detected Bo_ParVs in 10 out of 158 bovine fecal samples tested using real-time RT-PCR, and Bo_ParVs were isolated from three of these samples using MA104 cells. Analysis of the P1 region revealed that Bo_ParVs shared high pairwise amino acid sequence similarity (≥ 95.7% identity), suggesting antigenic similarity among Bo_ParVs, whereas nucleotide sequence identity values (≥ 84.8%) indicated more variability. A recombination breakpoint was identified in the 2B region, which may influence the evolution of this virus.
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