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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
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Anticoagulant management during percutaneous coronary intervention for a patient with antithrombin deficiency

Shun Kitamura1, Kota Komiyama1, Kazuyuki Yahagi1

  • 1Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.

Journal of Cardiology Cases
|February 15, 2023
PubMed

Insights

This case study details a successful cardiac intervention for a patient with antithrombin deficiency and acute coronary syndrome. The strategy involved heparin and antithrombin concentrate, preventing complications.

Area of Science:

  • Cardiology
  • Hematology

Background:

  • Antithrombin deficiency is a rare condition with limited data on cardiac interventions.
  • Managing anticoagulation during percutaneous coronary intervention (PCI) in these patients presents unique challenges.

Observation:

  • A 62-year-old male with a history of thrombosis presented with acute coronary syndrome (ACS).
  • Diagnosis included elevated troponin T, indicating acute myocardial infarction.
  • The patient had known antithrombin deficiency.

Findings:

  • Coronary intervention was performed using a combination of heparin and antithrombin concentrate.
  • The procedure was successful, with no reported thrombosis or bleeding complications.

Implications:

  • This case provides a potential anticoagulant management strategy for PCI in patients with antithrombin deficiency.
  • The findings may guide future clinical decisions and research in managing this rare patient population.

Keywords:
Acute coronary syndromeAntithrombin deficiency

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