Cancer, diabetes, survival and glycemic control: a large multisite analysis
Nina J Karlin1, Heidi E Kosiorek2, Patricia M Verona3
1Division of Hematology & Medical Oncology, Mayo Clinic, Phoenix, Arizona, USA.
Aim:
To determine overall survival (OS) and glycemic control in patients with cancer and diabetes.
Materials & Methods:
Patients of our institution with breast, colon, lung, pancreas and prostate cancer were retrospectively reviewed. OS was compared between matched patients with and without diabetes, and changes in glucose value over time were assessed.
Results:
For 3934 patients each with and without diabetes, adjusted analysis showed no difference in OS according to diabetes status (hazard ratio: 1.07; 95% CI: 0.96-1.20). Mean glucose values decreased over time in patients with and without diabetes (p = 0.01).
Conclusion:
In this large study of patients with five common cancers, the co-occurrence of diabetes did not affect OS. Cancer did not adversely affect glucose levels.
Related Concept Videos
Cancer Survival Analysis
Oral Hypoglycemic Agents: Biguanides and Glitazones
Comparing the Survival Analysis of Two or More Groups
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Diabetes Mellitus: Type 2 and Gestational
Hypoglycemia and Glucagon


