Epithelioid sarcoma and its outcome: a retrospective analysis from a tertiary care center in North India
Divya Kashyap1, Sameer Rastogi1, Vikas Garg1
1Department of Medical Oncology, AIIMS, New Delhi, 110029, India.
Aim:
Clinicopatholgical findings and outcomes in epithelioid sarcoma (ES) patients.
Materials & Methods:
ES patients registered in sarcoma clinic from 2015 to 2021.
Results:
There were 20 patients with median age of 26 years. Majority had distal ES (70%) and advanced disease (85%). In patients with advanced disease lymph nodes were involved in 65%, lungs in 58% and others in 35%. Among 14 patients who underwent biopsy outside our institute, nine (64.2 %) had been initially misdiagnosed. Response rates to doxorubicin (n = 12), pazopanib (n = 6), gemcitabine/docetaxel (n = 5), tazemetostat (n = 3) and immunotherapy (n = 2) used in various lines were 16, 16, 20, 33 and 0%, respectively.
Conclusion:
Our patients had an advanced-stage and distal ES, with a modest response to chemotherapy.
