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Co-infection associated with SARS-CoV-2 and their management
Vivek P Chavda1, Aayushi B Patel2, Anjali Pandya3
1Department of Pharmaceutics & Pharmaceutical Technology, L M College of Pharmacy, Ahmedabad, Gujarat, 380009, India.
Future Science OA
|February 15, 2023
Summary
This review details long COVID complications, including organ damage and rare infections like mucormycosis. It also discusses risk factors and treatments for post-COVID-19 conditions and multisystem inflammatory syndrome in children (MIS-C).
Area of Science:
- Infectious Diseases
- Public Health
- Internal Medicine
Background:
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused a global pandemic, leading to COVID-19.
- Many patients experience persistent symptoms and complications after acute infection, a condition known as long COVID.
- Unusual post-recovery illnesses and multisystem inflammatory syndrome in children (MIS-C) have been observed.
Purpose of the Study:
- To review the spectrum of issues following COVID-19 recovery.
- To identify risk factors associated with multiorgan damage.
- To explore treatment strategies for post-COVID-19 complications.
Main Methods:
- This is a review article.
- Literature search on COVID-19, long COVID, and associated conditions.
- Synthesis of information on reported cases, risk factors, and treatments.
Main Results:
- Post-COVID-19 recovery can involve persistent symptoms, multiorgan damage, and rare infections (e.g., mucormycosis, white fungus).
- "Happy hypoxia" and other systemic abnormalities are reported in recovered individuals.
- Multisystem inflammatory syndrome in children (MIS-C) is a significant concern.
Conclusions:
- Factors like uncontrolled steroid use, immunosuppression, diabetes, and inadequate post-recovery care may contribute to complications.
- Understanding and managing these diverse post-COVID-19 conditions is crucial.
- Further research is needed to elucidate mechanisms and optimize treatment for long COVID and MIS-C.
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