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Cutaneous Verrucous Carcinomas: A Review.

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Cutaneous verrucous carcinoma (CVC) is a rare skin cancer that can be mistaken for other conditions. This review clarifies its diagnosis, treatment, and the importance of careful follow-up to ensure proper patient management.

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • Verrucous carcinoma (VC) is a rare, slow-growing squamous cell carcinoma.
  • Cutaneous verrucous carcinoma (CVC) primarily affects the skin, often the feet.
  • CVC diagnosis is challenging due to its resemblance to benign and malignant conditions.

Purpose of the Study:

  • To review the pathogenesis and clinicopathologic features of CVC.
  • To discuss differential diagnosis and treatment options for CVC.
  • To provide management recommendations and emphasize follow-up care.

Main Methods:

  • Literature review of CVC pathogenesis.
  • Analysis of clinicopathologic features of CVC.
  • Evidence-based discussion of diagnostic and therapeutic strategies for CVC.

Main Results:

  • CVC presents diagnostic challenges, often confused with giant condyloma acuminata, keratoacanthoma, and squamous cell carcinoma.
  • Understanding CVC's unique features is crucial for accurate diagnosis.
  • Effective management requires distinguishing CVC from other skin lesions.

Conclusions:

  • Accurate diagnosis of CVC is essential to avoid inappropriate treatment.
  • Specific management strategies and careful follow-up are recommended for CVC.
  • Further research may improve understanding and treatment of CVC.