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Updated: Aug 10, 2025

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells
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ERCC6L2-related disease: a novel entity of bone marrow failure disorder with high risk of clonal evolution

Francesco Baccelli1, Davide Leardini2, Sara Cerasi1

  • 1Pediatric Oncology and Hematology Unit "Lalla Seràgnoli", IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Giuseppe Massarenti, 11, 40138, Bologna, Italy.

Annals of Hematology
|February 15, 2023
PubMed

Keywords:
Acute myeloid leukemiaCancer predispositionERCC6L2Hematopoietic stem cell transplantationMyelodysplastic syndrome

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