[Neuroleptic malignant syndrome - unexpected complication in a COVID-19 patient]

Jiří Sagan1, Martin Hýža, Tomáš Skřont

  • 1Department of Infectious Diseases, Faculty Hospital Ostrava and Faculty of Medicine, University of Ostrava, Czech Repubic,

Insights

Neuroleptic malignant syndrome is a rare but life-threatening condition. Early recognition and treatment are crucial, especially in patients with COVID-19 and those on antipsychotic medications.

Area of Science:

  • Medicine
  • Infectious Diseases
  • Psychiatry

Background:

  • Neuroleptic malignant syndrome (NMS) is a rare, life-threatening condition associated with antipsychotic medication.
  • While typically seen in psychiatric settings, NMS can present in infectious disease wards.
  • Infectious disease specialists must consider NMS in patients with psychiatric medication history and characteristic symptoms.

Observation:

  • A case of NMS occurred in a young male patient with schizophrenia admitted for COVID-19.
  • The patient developed NMS symptoms after receiving antipsychotics for restlessness.
  • This highlights the potential for NMS in critically ill patients on psychiatric medication.

Findings:

  • The patient presented with hyperthermia, rigidity, autonomic lability, and impaired consciousness.
  • Prompt, targeted therapy was initiated in collaboration with psychiatric specialists.
  • The patient's NMS symptoms resolved, and his clinical condition improved.

Implications:

  • This case underscores the importance of considering NMS in diverse clinical settings, including infectious disease and intensive care units.
  • Collaboration between infectious disease and psychiatric teams is vital for effective NMS management.
  • Awareness of NMS in patients with COVID-19 and on antipsychotics can improve patient outcomes.

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