Morphology, Solid Structure and Antioxidant Activity in Vitro of Angelica sinensis Polysaccharide-Ce(IV)

Angelica Sinensis polysaccharide cerium (ASP-Ce) was prepared by Angelica Sinensis polysaccharide (ASP) and cerium ammonium nitrate (NH₄ )₂ Ce(NO₃ )₆ . and its morphology, and solid structure was investigated. The antioxidant activity of the ASP-Ce complex in vitro was evaluated. The antioxidant activity of ASP-Ce complex in vitro was evaluated by the scavenging activity of 2,2-diphenyl-1-picrylhyrazyl radical (DPPH), hydroxyl radical (⋅OH) and superoxide anion radical ( $$ ⋅). The results showed that the ASP-Ce had the more ordered structure for inserting the Ce⁴⁺ into the polymer chain of ASP and there was little change in the conformation of the polysaccharide from Ce⁴⁺ . Three free radical scavenging experiments proved that ASP-Ce had better antioxidant capacity than of ASP, especially on DPPH, and then on $$ ⋅. The scavenging rate of ASP-Ce at 1.0 mg/mL on DPPH reached 71.6 %. Therefore, these results provide references for the further development and utilization of rare earth-polysaccharide.