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Updated: Aug 9, 2025

Quantification of Hypopigmentation Activity In Vitro
Published on: March 6, 2019
Segmental Pigmentation Disorder: A Case Report of Hypopigmented Patch
Ammar Bakhsh1, Khalid Al Hawsawi2, Ola Y Bahadur3
1Medicine and Surgery, Umm Al-Qura University, Makkah, SAU.
Abstract:
A segmental pigmentation disorder (SPD) is a form of pigmentary mosaicism. SPD is a hypo- or hyperpigmented patch that has a segmental pattern. A 16-year-old male with an insignificant past medical history presented with symptomless, slowly progressive skin lesions since early childhood. Skin examination revealed well-demarcated, non-scaling, hypopigmented patches on the right upper extremity. A similar spot was located on his right shoulder. Wood's lamp examination showed no enhancement. Differential diagnoses included segmental pigmentation disorder and segmental vitiligo (SV). A skin biopsy was obtained, which revealed normal findings. Based on the above clinicopathological findings, a diagnosis of segmental pigmentation disorder was made. The patient did not receive any treatment but was reassured that he did not have vitiligo.
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